Results from Clinical trials show
How does it work?
Made from a proprietary extract of Alpinia galanga, enXtra targets a cognitive process known as “Attention Network Function” (ANF), which is the ability of the brain to allocate processing resources to a specific task. The ANF system plays a critical role in mental alertness and the ability to focus on a task. Mechanism of action: A molecular docking study of enXtra demonstrated that its phytoconstituents may interact with neurotransmitters such as dopamine and acetylcholinesterase that play a role in alertness and focus.
Study
Vitamin B7 (Biotin) 1
SCIENTIFIC EVIDENCE
Vitamin B7 plays an important role in cell regulation which is crucial for the brain via neurotransmitters. This has led to studies focusing on how B vitamins play a regulatory role in memory and learning.
| CLAIM / STUDY | RESOURCE |
|---|---|
| Contributes to normal psychological function | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1728 |
| Contributes to normal functioning of the nervous system | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1728 |
| Contributes to the maintenance of normal mucous membranes | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2010.1728 |
| The protective effect of biotin supplementation and swimming training on cognitive impairment and mental symptoms in a rat model of Alzheimer's disease: A behavioural, biochemical, and histological study | https://www.cell.com/heliyon/fulltext/S2405-8440(24)08330-0 |
Vitamin B5 (Pantothenic Acid)
SCIENTIFIC EVIDENCE
This is one of the B vitamins critical in the formation of Co-enzyme A, that helps enzymes in the body to function and for general energy production. Studies look into the role that pantothenic acid has in the synthesis of neurotransmitters.
| CLAIM / STUDY | RESOURCE |
|---|---|
| Pantothenic acid contributes to normal mental performance (Mental Performance) | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1218 |
| Reduction of tiredness and fatigue | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1218 |
| Pantothenic acid contributes to the normal synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters | https://www.efsa.europa.eu/en/efsajournal/pub/1218 |
| Cerebral deficiency of vitamin B5 (d-pantothenic acid; pantothenate) as a potentially reversible cause of neurodegeneration and dementia in sporadic Alzheimer's disease | https://pubmed.ncbi.nlm.nih.gov/32416962 |
| Major involvement of Na(+) -dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells | https://www.ncbi.nlm.nih.gov/pubmed/25809983 |
| Pantothenic acid transport and metabolism in the central nervous system | https://www.ncbi.nlm.nih.gov/pubmed/3080905 |
| Development and Characterisation of Pantothenic Acid Transport in Brain | https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1471-4159.1986.tb04536.x |
| Vitamin transport and homeostasis in mammalian brain: focus on Vitamins B and E | https://www.ncbi.nlm.nih.gov/pubmed/17645457/ |
| B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ |
Pine Bark Extract
SCIENTIFIC EVIDENCE
Research suggests that Pine Bark enhances brain function through antioxidant support and improved cerebral blood flow.
| CLAIM / STUDY | RESOURCE |
|---|---|
| Helps to maintain good health by protecting cells & tissues through its antioxidant property. | https://www.gov.uk/government/publications/on-hold-health-claims-on-foods |
Bacopa Extract
SCIENTIFIC EVIDENCE
Bacopa monnieri is commonly used in Ayurvedic medicine. Studies investigate the impact it is thought to have on cognitive function, memory, stress relief, anxiety, general mood and vitality.
| CLAIM / STUDY | RESOURCE |
|---|---|
| The clinically-tested supplement that supports your health & beauty around the clock, delivering the right nutrients at the right time one. | Link goes here |
| The clinically-tested supplement that supports your health & beauty around the clock, delivering the right nutrients at the right time two. | Link goes here |
| The clinically-tested supplement that supports your health & beauty around the clock, delivering the right nutrients at the right time three. | Link goes here |
Lions Mane
SCIENTIFIC EVIDENCE
This mushroom has recently gained popularity for its potential neuroprotective and antioxidant properties. This has prompted experts to look at its potential for neurogenerative conditions and cognitive decline.
| CLAIM / STUDY | RESOURCE |
|---|---|
| Reduction of depression and anxiety by 4 weeks Hericium erinaceus (Lions Mane) intake | https://pubmed.ncbi.nlm.nih.gov/20834180 |
| Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia | https://pubmed.ncbi.nlm.nih.gov/24266378 |
| Neurohealth Properties of Hericium erinaceus (Lions Mane) Mycelia Enriched with Erinacines | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987239 |
| Hericium erinaceus (Lions Mane), an amazing medicinal mushroom | https://link.springer.com/article/10.1007/s11557-015-1105-4 |
| Hericium erinaceus (Lions Mane): an edible mushroom with medicinal values | https://www.degruyter.com/document/doi/10.1515/jcim-2013-0001/html |
| Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial | https://pubmed.ncbi.nlm.nih.gov/18844328 |
| Improvement of cognitive functions by oral intake of Hericium erinaceus | https://pubmed.ncbi.nlm.nih.gov/31413233 |
| Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake | https://pubmed.ncbi.nlm.nih.gov/20834180 |
| Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? | https://pubmed.ncbi.nlm.nih.gov/31118969 |
| Therapeutic Potential of Hericium erinaceus for Depressive Disorder | https://pubmed.ncbi.nlm.nih.gov/31881712 |
Iron
SCIENTIFIC EVIDENCE
Iron is an essential element for brain development and function. Studies focus on neurotransmitter synthesis, uptake and degradation. All of which are involved in behaviour, memory, learning and sensory systems.
| CLAIM / STUDY | RESOURCE |
|---|---|
| Iron contributes to normal cognitive function | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1215 |
| Iron has a role in the process of cell division | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1215 |
| Iron contributes to normal formation of red blood cells and haemoglobin | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1215 |
| Iron contributes to the reduction of tiredness and fatigue | https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1215 |
| Iron deficiency and common neurodevelopmental disorders | https://pubmed.ncbi.nlm.nih.gov/36173945 |
| Iron deficiency in Attention-Deficit Hyperactivity disorder, Autism spectrum disorder, internalizing and externalizing disorders, and movement disorders | https://pubmed.ncbi.nlm.nih.gov/37147046 |
| Iron and attention-deficit/hyperactivity disorder: What is the empirical evidence so far? A systematic review of the literature | https://pubmed.ncbi.nlm.nih.gov/23082739 |
| Could treatment of iron deficiency both improve ADHD and reduce cardiovascular risk during treatment with ADHD drugs? | https://pubmed.ncbi.nlm.nih.gov/22632845 |
| Effect of Oral Iron Supplementation on Cognitive Function among Children and Adolescents in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis | https://pubmed.ncbi.nlm.nih.gov/36558491 |
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